Thursday, November 28, 2019
Antigone vs. Ismene
The play revolves around a family of four siblings, two brothers and two sisters bereaved of their parents. It follows that Eteocles the younger brother to the two sisters engage in a fierce battle with Polinices his older brother over who is to rule Thebes.Advertising We will write a custom essay sample on Antigone vs. Ismene specifically for you for only $16.05 $11/page Learn More Both lose their lives and Creon their uncle assumes position of power. Creon declares that Eteocles is to be given a state funeral but outlaws the burial of polinices who in any case was the offended party as he had every right to rule Thebes. Antigone the last of Cadmus family that was riddled with tragedy defies the kingââ¬â¢s order against her sisterââ¬â¢s advice and goes ahead to burry her brother. The events that follow clearly indicate how abuse of power by a reckless ruler can lead to oppression of women who often suffer in silence unable to act and the resulting consequence to a society that does not listen to the voice of its women. Ismene is quick to stop her sister from carrying out her intention of defying the kingââ¬â¢s order without success. She goes ahead to tell her sister that in a society dominated by men, it would only be prudent as a woman to follow orders given by men however unreasonable they may seem. Ismenes position reflects the role that women were supposed to play in that society (Sayre 12). Creon is so offended by this action and he states that if the culprit is not brought to justice, the culprit would be the man and he the woman as he took it to be completely improper for a woman to defy orders given by a man. Antigone was stubborn to the point of her death. Traditionally, few women would defy men but in the recent times, women of courage have taken steps to defy stereotypes that often limit their potential. Like Antigone, their attempt to do the right thing is often met with resistance but their courage has often seen them prevail (Sayre 97). For instance, in the recent times there has been an increase of women in leadership positions. The play demonstrates that true courage grows stronger on opposition. Antigoneââ¬â¢s convictions are so strong that her sister decides to join her in her execution. Haemon the Kingââ¬â¢s son who was betrothed to Antigone follows suit and tries to talk his father out of his folly.Advertising Looking for essay on art and design? Let's see if we can help you! Get your first paper with 15% OFF Learn More The entire Thebes community knows Antigone is right but they cannot proclaim this in the open due to fear of offending their king. Teiresias the blind prophet tries to talk the king out of his folly but his arrogance which allows him to look down on women has blindfolded him and he only acts when it is too late. His recklessness leads Antigone to kill herself and his son commits suicide. Her wife Eurydice who comes much later does not talk much . On learning about her sonââ¬â¢s death, we are told that she ââ¬Å"silentlyâ⬠gets away and later commits suicide. The appearance of the queen at the end of the play and her silence is symbolic how women leadership was suppressed then. T he Play teaches that in a society whose leaders do not listen to the voice of reason or conscience by consistently looking down on women, such a society is likely to face tragic failure if women are not given equal chance with men. If the queenââ¬â¢s voice mattered, such chaos would not have taken place. Works Cited Sayre, Henry. The Humanities: Culture, Continuity and Change 1st edition. New Jersey: Prentice Hall. 2008. Print. Sayre, Henry. The Humanities: Culture, Continuity and Change 2nd edition. New Jersey: Prentice Hall. 2011. Print. This essay on Antigone vs. Ismene was written and submitted by user Dax G. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.
Sunday, November 24, 2019
Biography of Louis Armstrong, Masterful Trumpeter
Biography of Louis Armstrong, Masterful Trumpeter Louis Armstrong (August 4, 1901ââ¬âJuly 6, 1971) was born into poverty at the turn of the 20th century but rose above his humble origins to become a masterful trumpet player and beloved entertainer. He played a key role in the development of one of the early 20th centurys most important new styles of music: jazz. Armstrongs inventiveness and improvisational techniques, along with his energetic, dazzling style have influenced generations of musicians. One of the first to perform scat-style singing, he is also well-known for his distinctive, gravelly singing voice. Armstrong wrote two autobiographies and appeared in more than 30 films. Fast Facts: Louis Armstrong Known For: World-famous trumpeter and entertainer; he was influential in the development of jazz and also appeared in more than 30 filmsAlso Known As: Satchmo, Ambassador SatchBorn: August 4, 1901 in New OrleansParents: Mary Ann, William ArmstrongDied: July 6, 1971 in New York CityTop Albums: Ella and Louis, New Orleans Nights, Satchmo Musical Autobiography, Under the Stars, Porgy and Bess, Iââ¬â¢ve Got the World on a StringAwards and Honors: 1964 Grammy for Best Male Vocal Performance (Hello Dolly), Grammy Hall of Fame (various years), Rock and Roll Hall of Fame (inducted 2019)Spouses: Daisy Parker (m.à 1918-1923), Lili Hardin Armstrong (m.à 1924-1938), Alpha Smith (m.à 1938-1942), Lucille Wilson (m.à 1942-1971)Notable Quote: If you have to ask what jazz is, youll never know. Early Life Louis Armstrong was born in New Orleans on August 4, 1901, to 16-year-old Mary Ann Albert and her boyfriend Willie Armstrong. Only weeks after Louis birth, Willie left Mary Ann and Louis was placed in the care of his grandmother, Josephine Armstrong. Josephine brought in some money doing laundry for white families but struggled to keep food on the table. Young Louis had no toys, very few clothes, and went barefoot most of the time. Despite their hardships, Josephine made sure her grandson attended school and church. While Louis was living with his grandmother, his mother briefly reunited with Willie Armstrong and gave birth to a second child, Beatrice, in 1903. While Beatrice was still very young, Willie once again left Mary Ann. Four years later, when Armstrong was 6 years old, he moved back in with his mother, who was then living in a tough neighborhood called Storyville. It became Louisââ¬â¢ job to look after his sister. Working on the Streets By the age of 7, Armstrong was looking for work wherever he could find it. He sold newspapers and vegetables and made a little money singing on the street with a group of friends. Each group member had a nickname; Louis was Satchelmouth (later shortened to Satchmo), a reference to his wide grin. Armstrong saved up enough money to buy a used cornet (a brass musical instrument similar to a trumpet), which he taught himself to play. He quit school at age 11 to concentrate on earning money for his family. While performing on the street, Armstrong and his friends came into contact with local musicians, many of whom played in Storyville honky-tonks (bars with working-class patrons, often found in the South). Armstrong was befriended by one of the citys best-known trumpeters, Bunk Johnson, who taught him songs and new techniques and allowed Louis to sit in with him during performances in the honky-tonks. Armstrong managed to stay out of trouble until an incident on New Years Eve 1912 changed the course of his life. The Colored Waifs Home During a New Years Eve street celebration at the end of 1912, 11-year-old Louis fired a pistol into the air. He was hauled off to the police station and spent the night in a cell. The next morning, a judge sentenced him to the Colored Waifs Home for an unspecified period of time. The home, a reformatory for troubled black youths, was run by a former soldier, Captain Jones. Jones provided discipline as well as regular meals and daily classes, all of which had a positive effect on Armstrong. Eager to participate in the homes brass band, Armstrong was disappointed that he was not allowed to join right away. The band director surmised that a boy from Storyville who had fired a gun did not belong in his band. Armstrong proved the director wrong as he worked his way up the ranks. He first sang in the choir and later was assigned to play various instruments, eventually taking over the cornet. Having demonstrated his willingness to work hard and act responsibly, Louis was made the leader of the band. He reveled in this role. In 1914, after 18 months at the Colored Waifs Home, Armstrong returned home to his mother. Becoming a Musician Back home, Armstrong delivered coal during the day and spent his nights in local dance halls listening to music. He became friends with Joe King Oliver, a leading cornet player, and ran errands for him in return for cornet lessons. Armstrong learned quickly and began to develop his own style. He filled in for Oliver at gigs and gained further experience playing in parades and funeral marches. When the U.S. entered World War I in 1917, Armstrong was too young to participate, but the war did indirectly affect him. When several sailors stationed in New Orleans became victims of violent crime in the Storyville district, the secretary of the Navy shut down the district, including brothels and clubs. While a large number of New Orleans musicians moved north, many relocating to Chicago, Armstrong stayed and soon found himself in demand as a cornet player. By 1918, Armstrong had become well-known on the New Orleans music circuit, playing at numerous venues. That year, he met and married Daisy Parker, a prostitute who worked in one of the clubs he played in. Leaving New Orleans Impressed by Armstrongs natural talent, band conductor Fate Marable hired him to play in his riverboat band on excursions up and down the Mississippi River. Armstrong convinced Daisy that it was a good move for his career and she agreed to let him go. Armstrong played on the riverboats for three years. The discipline and high standards that he was held to made him a better musician; he also learned to read music for the first time. Yet, chafing under Marables strict rules, Armstrong grew restless. He yearned to strike out on his own and find his unique style. Armstrong quit the band in 1921 and returned to New Orleans. He and Daisy divorced that year. Earns a Reputation In 1922, a year after Armstrong quit the riverboats, King Oliver asked him to come to Chicago and join his Creole Jazz Band. Armstrong played the second coronet and was careful not to outshine bandleader Oliver. Through Oliver, Armstrong met the woman who became his second wife, Lil Hardin, who was a classically trained jazz pianist from Memphis. Lil recognized Armstrongs talent and thus urged him to break away from Olivers band. After two years with Oliver, Armstrong quit the band and took a new job with another Chicago band, this time as the first trumpet; however, he only stayed a few months. Armstrong moved to New York City in 1924 at the invitation of bandleader Fletcher Henderson. (Lil did not accompany him, preferring to stay at her job in Chicago.) The band played mostly live gigs but made recordings as well. They played backup for pioneering blues singers such as Ma Rainey and Bessie Smith, furthering Armstrongs growth as a performer. Just 14 months later, Armstrong moved back to Chicago at Lils urging; Lil believed that Henderson held back Armstrongs creativity. The Worlds Greatest Trumpet Player Lil helped to promote Armstrong in Chicago clubs and billing him as the worlds greatest trumpet player. She and Armstrong formed a studio band, called Louis Armstrong and His Hot Five. The group recorded several popular records, many of which featured Armstrongs raspy singing. On one of the most popular of the recordings, Heebie Jeebies, Armstrong spontaneously launched into scat-singing, in which the singer replaces the actual lyrics with nonsense syllables that often mimic the sounds made by instruments. Armstrong did not invent the singing style but helped to make it enormously popular. During this time, Armstrong permanently switched from cornet to trumpet, preferring the brighter sound of the trumpet to the more mellow cornet. The records gave Armstrong name recognition outside of Chicago. He returned to New York in 1929, but again, Lil did not want to leave Chicago. (They stayed married but lived apart for many years before divorcing in 1938.) In New York, Armstrong found a new venue for his talents; he was cast in a musical revue that featured the hit song Aint Misbehavin and Armstrongs accompanying trumpet solo. Armstrong displayed showmanship and charisma, gaining a greater following after the show. The Great Depression Because of the Great Depression, Armstrong, like many others, had trouble finding work. He decided to make a new start in Los Angeles, moving there in May 1930. Armstrong found work in clubs and continued to make records. He made his first film, Ex-Flame, appearing as himself in the movie in a small role. Armstrong gained more fans through this widespread exposure. After an arrest for marijuana possession in November 1930, Armstrong received a suspended sentence and returned to Chicago. He stayed afloat during the Depression, touring the U.S. and Europe from 1931 to 1935. Armstrong continued to tour throughout the 1930s and 1940s and appeared in a few more movies. He became well-known not only in the U.S. but in much of Europe as well, even playing a command performance for King George V of England in 1932. Big Changes In the late 1930s, band leaders such as Duke Ellington and Benny Goodman helped to propel jazz into the mainstream, ushering in the swing music era. The swing bands were large, consisting of about 15 musicians. Although Armstrong preferred working with smaller, more intimate ensembles, he formed a large band in order to capitalize on the swing movement. In 1938, Armstrong married longtime girlfriend Alpha Smith, but soon after the wedding he began seeing Lucille Wilson, a dancer from the Cotton Club. Marriage No. 3 ended in divorce in 1942 and Armstrong took Lucille as his fourth (and final) wife the same year. While Armstrong toured, often playing at military bases and army hospitals during World War II, Lucille found them a house in her hometown of Queens, New York. After years of traveling and staying in hotel rooms, Armstrong finally had a permanent home. Louis and the All-Stars In the late 1940s, large bands were falling out of favor, deemed too expensive to maintain. Armstrong formed a six-piece group called Louis Armstrong and the All-Stars. The group debuted at New Yorks Town Hall in 1947, playing New Orleans styled jazz to rave reviews. Not everyone enjoyed Armstrongs somewhat hammy brand of entertainment. Many from the younger generation considered him a relic of the Old South and found his mugging and eye-rolling racially offensive. He was not taken seriously by young up-and-coming jazz musicians. Armstrong, however, saw his role as more than that of a musician: he was an entertainer. Continued Success and Controversy Armstrong made 11 more movies in the 1950s. He toured Japan and Africa with the All-Stars and recorded his first singles. Armstrong faced criticism in 1957 for speaking out against racial discrimination during the episode in Little Rock, Arkansas, in which black students were heckled by whites while attempting to enter a newly integrated school. Some radio stations even refused to play his music. The controversy faded after President Dwight Eisenhower sent federal troops to Little Rock to facilitate integration. On tour in Italy in 1959, Armstrong suffered a massive heart attack. After a week in the hospital, he flew back home. Despite warnings from physicians, Armstrong returned to a busy schedule of live performances. Later Years and Death After playing five decades without a No. 1 song, Armstrong finally made it to the top of the charts in 1964 with Hello Dolly, the theme song for the Broadway play of the same name. The popular song knocked the Beatles from the top spot they had held for 14 consecutive weeks. By the late 1960s, Armstrong was still able to perform, despite kidney and heart problems. In the spring of 1971, he suffered another heart attack. Unable to recover, Armstrong died July 6, 1971, at age 69. More than 25,000 mourners visited the body of Louis Armstrong as it lay in state and his funeral was televised nationally. Sources ï » ¿Ã¢â¬Å"Louis Armstrong - Awards and Honors.â⬠à JazzSkool.org.Britannica, The Editors of Encyclopaedia. ââ¬Å"Louis Armstrong.â⬠à Encyclopà ¦dia Britannica, Encyclopà ¦dia Britannica, Inc., 14 Feb. 2019.ââ¬Å"Bop to the Best of Louis Armstrong | UDiscover Music.â⬠à UDiscoverMusic.
Thursday, November 21, 2019
Introduce a Company into Spain Essay Example | Topics and Well Written Essays - 1000 words
Introduce a Company into Spain - Essay Example Figure 1: Predicted Mall Distribution Space in Spain The product will be distributed through a long distribution channel whereby several middlemen will link the retailer with producers of different commodities. Although this kind of distribution channel may raise the price that the consumers will pay for the products, it will be essential to use it because the supermarkets will deal with a multiple of products and hence may not get time to deal with all the logistics of individual commodities ââ¬â this role will be left for the suppliers. All in all, the market is concentrated in the hands of few, and it is these domineering stores Coles is expected to compete with, which means that the competition will be quite stiff. The right media will be chosen to ensure the marketing plan is successful. Therefore, the communication channels will be based on their ability to convey the right message to the target audience in the most effective means. Coles will develop communication channels largely through direct mail, television, radio, as well as the internet. These channels will be used to show consumers how they will benefit by shopping from Coles supermarkets. The products that will be sold by Coles will also act as a channel of communication with the consumers. The Supermarket stores will serve as sources of instant information regarding the sales, available products, location of in-store products and methods of getting out-of-stock items. Generally, the supermarket will exploit channels such as addressable media, interactive media, and mass media. Coles will apply pull strategy, which involves the customers dynamically looking for the companyââ¬â¢s products while the retailers requesting for goods in response to direct consumer demand. This strategy will require Coles to establish a strong brand in Spain, which will be achieved through mass media promotions among other strategies of similar nature. In this view, when the supermarket identifies a certain prod uct that the consumers require, the management will ensure it is stocked ââ¬â this means that the supermarket will be charged with the responsibility of creating the demand while the supply channels will ensure that this demand is met. Coles will adopt a competition-based pricing strategy, whereby the setting of prices will be based on what the rival supermarket are charging (Cannon and Morgan 19). Business Review Coles supermarkets have operated for more than 90 years in Australia. The company has very rich history of Australia especially because it was founded by the founders of Australiaââ¬â¢s retail industry. Coles founder, George Coles, after studying best practices in retailing from the US went back to Australia in 1914 and opened stores in Melbourne, Collingwood and Smith Street. The company opened its first supermarket in 1960 in North Balwyn, Victoria. By 1973, Coles had managed to open stores in all the capital cities of Australia (Armstrong and Kotler 56). BI-LO is a chain of supermarket owned by Wesfarmers, which was previously known as Coles Group. BI-LO changed name to Coles Supermarkets during 2006 and 2007 when they attained 180 chains of stores. Following a poor performance of stores which had been converted
Wednesday, November 20, 2019
Business Manangement Coursework Example | Topics and Well Written Essays - 500 words
Business Manangement - Coursework Example Social responsibility improves public relations, companies that are socially responsible tend to be more prolific as they can attract productive employees and retain quality workers, reduce bad publicity and risk from government litigation. However, social responsibility can also harm the business by interfering in the quest of profit maximization. This usually occurs because socially responsible actions can carry a very high cost, paid by the businesses indulging in corporate social responsibility. Business Ethics Business owners frequently make decisions involving ethical considerations. Contrasting decisions are made in similar situations by different managers, depending on their particular moral development, individual characteristics and the culture of their organization. In the case of ââ¬Å"Who To Lay Off?â⬠a questions approach can be employed according to Robbins, Coulter, and Vohra (2008) to identify ethical considerations. If the business owner asks himself questions such as ââ¬Å"have you defined the problem accurately?â⬠Robbins, Coulter, and Vohra (2008,p.108) He can decide as to whether or not terminating an employee is the most ethical decision.
Monday, November 18, 2019
E-Commerce and the Value Proposal Essay Example | Topics and Well Written Essays - 6000 words
E-Commerce and the Value Proposal - Essay Example The platform of e-commerce has emerged as one of the popular modes of performing related operations of retail chain businesses in an electric form. Notably, the activities in e-commerce include performing operations and making transactions with the use of internet. For several businesses, the platform of e-commerce is also used for gathering relevant information about consumer market and competitorsââ¬â¢ actions amid the prime ones. The rationale behind conducting this study was to explore the benefits and identifying the challenges that Sainsburyââ¬â¢s experienced with respect to introduction of e-commerce in its business process. Besides, further supporting the assessment of the identified issues, certain recommendations has been made that will certainly assist the business of Sainsburyââ¬â¢s to improve its operational process. Considering the fact that the platform of e-commerce has emerged as one of the beneficial approaches to reach more customers in highly conventional setting thus, apparently, the prospective to conduct this study was to explore e-commerce trend in the global retail market. Along with this prospect, the significance of conducting the study also laid in exploring the issues that Sainsburyââ¬â¢s faced within aggressive e-commerce trend in the marketplace by other competitive businesses. Rationale after the study resolution to recognised the problems of the corporation that can be positively to sustenance the company in developing its commercial procedure. Appropriately, this study will support the company.
Friday, November 15, 2019
Assessment of Naproxen and Paracetamol in Mixed Tablet
Assessment of Naproxen and Paracetamol in Mixed Tablet METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ASSESSMENT OF NAPROXEN AND PARACETAMOL IN MIXED TABLET DOSAGE FORM BY RP-UPLC K.KANAKAPARVATHI*, Vijay Nagarjan, Santha Arcot and CH Hemanth Kumar. ABSTRACT An advancement design and corroboration for simultaneous assessment of Naproxen (NAP) and Paracetamol (PAR) in merged tablet dosage form by UPLC. The column used in determination was C18 thermo fisher (50cm x 4.6 mm x 3Ã µm), mobile phase used in this method was 0.4% ammonium acetate buffer: methanol: acetonitrile (40:40:20), the retention time was about 1.9 minutes and 3 minutes for PAR and NAP of a total run time of 5 minutes, with flow rate of 0.2ml per minute respectively at a wavelength of 271nm, linearity of the method was linear over the range of 38.496 to 57.664Ã ¼g/ml for Paracetamol and 64.096 to 95.968Ã ¼g/ml of Naproxen respectively with a correlation of 0.999 for simultaneous assessment for PAR and NAP thus the method was fast, simple, elegant and less time consuming method Keywords: Naproxen, Paracetamol RP-UPLC, Method validation INTRODUCTION Naproxen is chemically 2-Naphthaleneacetic acid, 6-methoxy-Ã ±-methyl-(s)-(+)-(s)-6 methoxy-Ã ±-methyl-2-naphthaleneacetic acid as shown in (Figure 1). It is a non-steroidal anti-inflammatory drug commonly used for minimizing of moderate to severe torment, delirium, inflammation and stiffness. [6-11]. Paracetamol (PAR) is chemically N-(4-hydroxyphenyl) acetamide (Figure 2), It has analgesic and antipyretic activity for the therapy of subsidiary, non-inflammatory conditions of patient who were prone to gastric symptoms [12-14]. The merger of these two drugs are used in the remedy [11] of Musculoskeletal Disorder (Sprain/Strains) Trauma Fractures/injuries), Occupational affliction, Joint torment, Low Back laceration the literature review supports legion UPLC methods for the evaluation of NAP and PAR independently and in combination with other drugs but There was no UPLC method had been reported for the determination of NAP and PARA in merged dosage form So an experiment was taken to expand and corroborate a rapid RP-UPLC method [1-5] for the determination of NAP and PARA in mixed tablet dosage forms. Figure 1 NAPROXEN Figure 2 Paracetamol MATERIALS NAP and PAR was earned from Ideal analytical and research institution puducherry, India. All chemicals worn were analytical standard. The pharmaceutical tablet dosage form used in this study was NAPROSYN P with a label claim of NAP 300mg and PAR 500mg were purchased from local pharmacy. INSTRUMENTATION AND APPARATUS The uplc system used for advancement design and corroboration was thermo accela equipped with 1050 quaternary pump auto sampler and photodiode array detector. The detector output were recorded and processed using chrome quest software version 5.0 sonicator (PCI bath sonicator ) was used for degassing of mobile phase and sonication of the solutions prepared SOFTWARE: The statically calculation for the analysis was performed by using Microsoft excel 2010 software (Microsoft, USA) METHOD CORROBORATION: SYSTEM SUITABILITY: System suitability was determined by injecting the standard solution and observed the parameters like retention time, peak area, relative standard deviation, tailing factor, USP theoretical plates. LINEARITY For testing of linearity five different concentration of sample solution (80%, 90%, 100%, 110%, and 120%) was injected and checked over by plotting the graph as peak area verses concentration thus the data treated by linear regression analysis. ACCURACY Accuracy can be done by injecting the sample solution with known standard concentration and the amount of percentage recovery gives the accuracy of sample. PRECISION Precision can be evaluated by Interday and intraday, were the same sample solution has to be assayed for the same day and on different days at different time intervals ROBUSTNESS The determination of robustness can be done by changing the experimental condition deliberately. The condition may include of changing in mobile phase flow rate, pH and temperature, the percentage of RSD, tailing factor, resolution, were cross check with the original data. RESULT DISCUSSION: The method has validated according to the norms of international harmonization of conference (ICH) guidelines with regards of system suitability, linearity, accuracy, precision and robustness as follows SYSTEM SUITABILITY The system suitability tests were carried out to evaluate the resolution and reproducibility of the system for the analysis. The results of the system suitability test were summarized in Table No.1. Table 1: System suitability results S.No PARAMETERS PAR NAP 1 Retention Time 1.807 3.007 2 Peak area 410801 306340 3 Percentage area 57.28 42.72 4 Theoretical plates 2633 3306 5 Resolution 0.0000 0.85712 6 Tailing factor 1.754 1.696 Solution stability The solvents which had been used in the mobile phase were cost effective than the solvents used in the other UPLC methods which are reported in the literatures. Standard and samples solution stability was studied above 12 and 24 hours and found stable against the freshly prepared standard. Table2. Results of Solution stability Time (hrs) Percentage Assay Percentage difference in assay PAR NAP PAR NAP Initial 99.92 99.99 0.002 0.001 After 12 hrs 99.52 99.57 0.003 0.002 After 24 hrs 99.12 99.19 0.001 0.002 LINEARITY Linearity of the method was evaluated at 5 different concentration levels of 38.496 to 57.664Ã ¼g/ml for Paracetamol and 64.096 to 95.968Ã ¼g/ml of Naproxen respectively. Both the drugs were found to give linear detector response in the concentration under study with correlation coefficient of 0.997 and 0.999 for PAR and NAP respectively. Table3: Linearity study for NAP and PAR S.NO PARAMETERS PAR NAP 1 Linearity range 38.49 57.664Ã ¼g/ml 64.09 -95.96Ã ¼g/ml 2 Correlation coefficient (r2) 0.997 0.999 3 Slope 3769.8726 2867.1591 4 Intercept 1567.7362 0.1591 ACCURACY Accuracy of the method was determined by recovery test. The percentage recovery was found to be within the concentration of 100 to 115 as 100, 105, 110, and 115 (Table4). All results indicate that the method is highly accurate. Table: 4(a) accuracy data for PAR S.NO ACCURACY LEVEL STANDARD AREA SAMPLE AREA Mg/tab PERCENTAGE 1 100 404871 393726 499.83 99.97 2 105 404871 413927 525.48 105.1 3 110 404871 433143 549.87 109.97 4 115 404871 454077 576.46 115.29 Table 4(b) accuracy data for NAP S.NO ACCURACY LEVEL STANDARD AREA SAMPLE AREA Mg/tab PERCENTAGE 1 100 306460.4 303506 299.26 99.75 2 105 306460.4 319467 315.00 105.00 3 110 306460.4 334246 329.57 109.86 4 115 306460.4 350847 345.94 115.31 PRECISION This method was validated for its inter-day and intra-day precision. The results (table4) obtained were within the acceptable limit. Table 5: results for precision studies s.no Parameter(units) PAR NAP STANDARD AREA SAMPLE AREA PERCENTAGE STANDARD AREA SAMPLE AREA PERCENTAGE 1 Interday precision (1st day) (2nd day) (3rd day) 404871 404871 404871 401886 402568 403442 100.87 99.28 100.74 306460 306460 306460 307076 307209 309589 99.77 98.08 100.07 2 Intraday precision 1sthrs 2nd hrs 3rd hrs 404871 404871 404871 402645 401507 400271 100.17 100.65 100.49 306460 306460 306460 309957 307438 307946 99.82 99.76 100.07 3 Average 100.366 99.595 4 SD 0.584 0.75 5 RSD 0.582 0.758 ROBUSTNESS The robustness of the method was determined and the percentage RSD of the results was found to be less than 2.0%, which demonstrate that the developed method is robust. Table6. Results of Robustness parameter CHANGED PARAMETERS FLOW RATE WAVE LENGTH S.NO PARAMETERS 190 210 269 273 PAR NAP PAR NAP PAR NAP PAR NAP 1 Retention time 1.938 3.215 1.70 2.832 1.810 3.005 1.810 3.007 2 Area 462947 347334 406134 306784 432154 322852 426295 347442 3 % area 57.13 42.87 56.97 43.03 57.24 42.76 55.10 44.90 CONCLUSION: Thus, the above stated method for determination of PAR and NAP by UPLC method concludes as it can be quantified simultaneously by using of isocratic mobile phase of 0.4% ammonium acetate buffer: methanol: acetonitrile (40:40:20), by using of PDA detector at 271 nm. Thus the proposed method is simple, precise, accurate, rapid and sensitive, where it can be applied successfully for the assessment of PAR and NAP in combined pharmaceutical formulations. ACKNOWLEDGEMENT The authors are thankful to ideal analytical and research laboratory pondycherry, India for all the facilities provided to complete our work.
Wednesday, November 13, 2019
Lacoste :: essays research papers
à à à à à Introduction Andaman Tourism Recovery Plan 2005 was developed by Tourism Authority of Thailand in order to manage the Crisis of ââ¬Å"Tsunamiâ⬠Tidal Wave, which mainly caused tremendous damages to 6 southern provinces of Thailand, which are Phuket, Phang Nga, Krabi, Ranong, Satun and Trang. This tidal wave not only affected to local people and thousands of tourists, who lost some of their family members and property in this natural disaster, but also many of tourism investors and service providers such as Hotels and accommodations, restaurants and travel agents lost their property and incomes as well. Since these 6 southern provinces of Thailand are located on coastal Andaman, they are very famous among tourists both Thai and foreigners for beautiful coasts and unspoiled nature. Each year, these provinces could bring a lot of tourists from everywhere to Thailand. The local people in theses areas earn their living mainly from selling souvenirs and providing tourism services to tourists. Therefore, when ââ¬Å"Tsunamiâ⬠tidal wave unexpectedly attacked and made many of tourists canceled or postponed the trip to Thailand, it causes the opportunity to restore the business and improve condition of living of local people after the Tsunami seem to be hopeless. Therefore, Andaman Tourism Recovery Plan 2005 will assist all stakeholders to know where Tourism Authority of Thailand is heading to in order to restore and develop these 6 southern provinces. In this report, we will study and analyze the recovery plan and evaluate the possibility to make all processes success according to the objectives, which Tourism Authority of Thailand set up. à à à à à à à à à à à à à à à à à à à à Ms. Ajaree Viwatpinyo à à à à à à à à à à I.D. 463 9605 à à à à à à à à à à à à à à à à à à à à Ms.Naiyana Vongfufeungkajornà à à à à I.D. à à à à à à à à à à à à à à à à à à à à à à à à à à à à à à Objectives -à à à à à To study the Andaman recovery plan 2005, developed by TAT. -à à à à à To analyze the positive and negative of impact from the recovery plan. -à à à à à To analyze the potential effectiveness of the recovery plan. -à à à à à To criticize the role of concerned organization in order to create the effectiveness of the plan. According to the tidal wave disaster ââ¬Å"Tsunamiâ⬠which attacked many countries around Andaman Sea on 26th of December 2004, 6 provinces in southern part of Thailand are one of the victims of this natural disaster. In consequence of ââ¬Å"Tsunamiâ⬠, the situation of tourism in Andaman coastal provinces of Thailand is facing the unexpected crisis. Moreover, the unclear information regarding the situation in affected areas leads to the decrease of number of tourist. For example, the disaster caused many tourists to cancel hotel bookings in Satun, even the province received only slight damage.
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